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Purchasing Controlled Substances: The CMF cannot sell controlled substances, they can administer them for a fee. A request for this service must be made in advance. If you will be using controlled substances in your research protocol, you will have to obtain both a State and Federal Research DEA number. This process takes several months to complete. The application and instructions for the State of Illinois Controlled Substances Research license can be found at . Once the Illinois license is approved, you may submit online for a Federal Research Controlled Substance license. Illinois applications are submitted on hard copy via the U.S. mail. Federal licenses are submitted online. Information for obtaining a Federal license can be found at .